5-[(4-Bromophenoxy)methyl]-1,3,4-thiadiazol-2-amine

5-[(4-Bromophenoxy)methyl]-1,3,4-thiadiazol-2-amine - Names and Identifiers

Name	5-(4-Bromo-Phenoxymethyl)-[1,3,4]Thiadiazol-2-Ylamine
Synonyms	5-[(4-Bromophenoxy)methyl]-1,3,4-thiadiazol-2-amine 1,3,4-Thiadiazol-2-aMine, 5-[(4-broMophenoxy)Methyl]- 5-(4-BROMO-PHENOXYMETHYL)-[1,3,4]THIADIAZOL-2-YLAMINE 5-(4-Bromo-Phenoxymethyl)-[1,3,4]Thiadiazol-2-Ylamine
CAS	299441-95-5

5-[(4-Bromophenoxy)methyl]-1,3,4-thiadiazol-2-amine - Physico-chemical Properties

Molecular Formula	C9H8BrN3OS
Molar Mass	286.15
Melting Point	180-182℃ (ethanol )
Storage Condition	2-8°C

5-[(4-Bromophenoxy)methyl]-1,3,4-thiadiazol-2-amine - Introduction

5-(4-Bromo-Phenoxymethyl)-[1,3,4]Thiadiazol-2-Ylamine is an organic compound with the molecular formula C10H9BrN4O2S. The following is a description of some of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 5-(4-Bromo-Phenoxymethyl)-[1,3,4]Thiadiazol-2-Ylamine is a white to light yellow crystalline powder.
-Solubility: Its solubility in water is low, but its solubility in organic solvents such as methanol, ethanol and dichloromethane is high.
-Melting point: Its melting point is about 180-182 ° C.

Use:
- 5-(4-Bromo-Phenoxymethyl)-[1,3,4]Thiadiazol-2-Ylamine is an important organic intermediate that can be used to synthesize other compounds.
-It is also used in the medical field, such as as antibacterial drugs.

Method:
The preparation of 5-(4-Bromo-Phenoxymethyl)-[1,3,4]Thiadiazol-2-Ylamine is usually carried out by the following steps:
1. P-Bromophenol reacts with sodium hypochlorite under alkaline conditions to generate 2-bromo phenol.
2. 2-bromo-benzoyl thiocyanate was synthesized by reacting 2-bromo-phenol with formyl thiocyanate under alkaline conditions.
3. React 2-bromo-benzoyl thiocyanate with ammonia in sodium bicarbonate solution to generate 5-(4-Bromo-Phenoxymethyl)-[1,3,4]Thiadiazol-2-Ylamine.

Safety Information:
5-(4-Bromo-Phenoxymethyl)-[1,3,4]Thiadiazol-2-Ylamine are generally organic synthesis intermediates and have certain risks. The following safety precautions should be paid attention to when using:
-This compound may be irritating and corrosive and requires protective measures when in contact with skin, eyes or respiratory tract.
-in the process of Operation should pay attention to avoid inhalation of dust or contact with the solution, the use of appropriate protective measures such as wearing protective glasses, gloves and protective mask.
-Should be in a well-ventilated place construction, and the use of chemical protective equipment.
-Avoid contact with strong oxidants and strong alkali substances to avoid dangerous reactions.

It should be noted that the information provided above is for reference only. Please consult the accurate data and safety information provided by the laboratory or chemical supplier before formal use.

Last Update：2024-04-09 19:05:48